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Chong, S.; Yoshida, S. R. (2024) "How transcription factor binding controls transcriptional bursting dynamics: A single-molecule view" Molecular Cell, 84, 997-999. †Corresponding author

Yoshida, S. R.; Chong, S. (2024) "Single-molecule measurement of protein interaction dynamics within biomolecular condensates" Journal of Visualized Experiments, 203, e66169. †Corresponding author


Chen, L.**†; Zhang, Z.**; Han, Q.*; Maity, B. K.*; Rodrigues, L.; Zboril, E.; Adhikari, R.; Ko, S-H.; Li, X.; Yoshida, S. R.; Xue, P.; Smith, E.; Xu, K., Wang, Q.; Huang, T. H-M.; Chong, S.; Liu, Z.† (2023) "Hormone-induced enhancer assembly requires an optimal level of hormone receptor multivalent interactionsMolecular Cell, 83, 3438-3456. †Corresponding author. *Equal contribution. **Equal contribution

This work is featured in a Q&A article in Molecular Cell, "Meet the authors: Lizhen Chen, Shasha Chong, and Zhijie “Jason” Liu".

Yoshida, S. R.; Maity, B. K.; Chong, S.† (2023) “Visualizing protein localizations in fixed cells: caveats and the underlying mechanismsThe Journal of Physical Chemistry B, 127, 4165-4173. †Corresponding author


Boeynaems, S.*; Chong, S.*; Gsponer, J.*; Holt, L.*; Milovanovic, D.*; Mitrea, D.*; Mueller-Cajar, O.*; Portz, B.*; Reilly, J.*; Reinkemeier, C.*; Sabari, B.*; Sanulli, S.*; Shorter, J.*; Sontag, E.*; Strader, L.*; Stachowiak, J.*; Weber, S.*; White, M.*;  Zhang, H.*; Zweckstetter, M.*; Elbaum-Garfinkle, S.; Kriwacki, R. (2023) "Phase separation in biology and disease; current perspectives and open questionsJournal of Molecular Biology, 435, 167971. *Equal contribution

Wang, X. Q. D.*; Fan, D.*; Han, Q.*; Liu, Y.*; Miao, H.; Wang, X.; Li, Q.; Chen, D.; Gore, H.; Himadewi, P.; Pfeifer, G. P.; Cierpicki, T.; Grembecka, J.; Su, J.; Chong, S.† ; Wan, L.†; Zhang, X.† (2023) "Mutant NPM1 hijacks transcriptional hub to maintain pathogenic gene programs in acute myeloid leukemia" Cancer Discovery, 13, 724-745. †Corresponding author. *Equal contribution


Irgen-Gioro, S.*; Yoshida, S. R.*Walling, V.; Chong, S. (2022) "Fixation can change the appearance of phase separation in living cells" eLife, 11, e79903. †Corresponding author. *Equal contribution

This work is featured in an Insight article in eLife, "Condensates: When fixation creates fiction".

Chong, S.; Graham, T. G. W.; Dugast-Darzacq, C.; Dailey, G. M.; Darzacq, X.; Tjian, R. (2022) "Tuning levels of low-complexity domain interactions to modulate endogenous oncogenic transcription" Molecular Cell, 82, 2084-2097.

This work is featured in a Previews article in Molecular Cell, "Regulating gene expression through control of transcription factor multivalent interactions", and selected for Faculty Opinions.

2007-2021 (Prior to Caltech)

Seong, B. K.; Dharia, N. V.; Lin, S.; Donovan, K. A.; Chong, S.; Robichaud, A.; Conway, A.; Hamze, A.; Ross, L.; Alexe, G.; Adane, B.; Nabet, B.; Ferguson, F.; Stolte, B.; Wang, E. J.; Sun, J.; Darzacq, X.; Piccioni, F.; Gray, N. S.; Fischer, E. S.; Stegmaier, K. (2021) “TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcomaCancer Cell, 39, 1262-1278.

Chong, S.†; Mir, M. (2021) "Towards decoding the sequence-based grammar governing the functions of intrinsically disordered protein regions" Journal of Molecular Biology, 433, 166724. †Corresponding author

Esbin, M. N.; Whitney, O. N.; Chong, S.; Maurer, A.; Darzacq, X.; Tjian, R. (2020) “Overcoming the Bottleneck to Widespread Testing: A Rapid Review of Nucleic Acid Testing Approaches for COVID-19 DetectionRNA, 26, 771-783. 

Wan, L.; Chong, S.*; Xuan, F.*; Liang, A.*; Cui, X.; Gates, L.; Carroll, T.; Li, Y.; Feng, L.; Chen, G.; Wang, S.-P.; Ortiz, M.; Daley, S.; Wang, X.; Xuan, H.; Kentsis, A.; Muir, T.; Roeder, R. G.; Li, H.; Li, W.; Tjian, R.; Wen, H.; Allis, C. D. (2020) “Impaired Cell Fate by Gain-of-Function Mutations in a Chromatin ReaderNature, 577, 121-126. *Equal contribution

Chong, S.; Dugast-Darzacq, C.; Liu, Z.; Dong, P.; Dailey, G. M.; Cattoglio, C.; Heckert, A.; Banala, S.; Lavis, L.; Darzacq, X.; Tjian, R. (2018) “Imaging Dynamic and Selective Low-Complexity Domain Interactions That Control Gene TranscriptionScience, 361, eaar2555. 

Chong, S.*; Chen, C.*; Ge, H.; Xie, X. S. (2014) “Mechanism of Transcriptional Bursting in BacteriaCell, 158, 314-326. *Equal contribution 

Kim, S.*; Broströmer, E.*; Xing, D.*; Jin, J.*; Chong, S.; Ge, H.; Wang, S.; Gu, C.; Yang, L.; Gao, Y. Q.; Su, X.; Sun, Y.; Xie, X. S. (2013) “Probing Allostery Through DNAScience, 339, 816-819. *Equal contribution

Chong, S.*; Min, W.*; Xie, X. S. (2010) “Ground-State Depletion Microscopy: Detection Sensitivity of Single-Molecule Optical Absorption at Room TemperatureThe Journal of Physical Chemistry Letters, 1, 3316-3322. *Equal contribution

Lu, S.*; Min, W.*; Chong, S.; Holtom, G. R. & Xie, X. S. (2010) “Label-Free Imaging of Heme Proteins with Two-Photon Excited Photothermal Lens MicroscopyApplied Physics Letters, 96, 113701. *Equal contribution

Min, W.*; Lu, S.*; Chong, S.; Roy, R.; Holtom, G. R. & Xie, X. S. (2009) “Imaging Chromophores with Undetectable Fluorescence by Stimulated Emission MicroscopyNature, 461, 1105-1109. *Equal contribution

Fu, Y.; Wang, H.-J.; Chong, S.; Guo, Q.-X. & Liu, L. (2009) “An Extensive Ylide Thermodynamic Stability Scale Predicted by First-Principle CalculationThe Journal of Organic Chemistry, 74, 810-819.

Shi, J.; Chong, S.; Fu, Y.; Liu, L. & Guo, Q.-X. (2008) “Ring Opening versus Ring Expansion in Rearrangement of Bicyclic Cyclobutylcarbinyl RadicalsThe Journal of Organic Chemistry, 73, 974-982.

Chong, S.; Fu, Y.; Liu, L. & Guo, Q.-X. (2007) “O-H Bond Dissociation Enthalpies of Oximes: A Theoretical Assessment and Experimental ImplicationsThe Journal of Physical Chemistry A, 111, 13112-13125.

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